Epigenetic mechanisms in cardiac development and disease
نویسندگان
چکیده
منابع مشابه
Epigenetic mechanisms in heart development and disease.
Suboptimal intrauterine development has been linked to predisposition to cardiovascular disease in adulthood, a concept termed 'developmental origins of health and disease'. Although the exact mechanisms underlying this developmental programming are unknown, a growing body of evidence supports the involvement of epigenetic regulation. Epigenetic mechanisms such as DNA methylation, histone modif...
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If one accesses the human genome websites, either the publicly or privately funded, and examines the information, one will find only the four letters A, G, T, and C in various combinations. However, one will not find a fifth letter we know to exist, namely C for 5-methylcytosine. For cancer research, this is a significant issue as alterations in DNA methylation in human cancer were first discov...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2011
ISSN: 1672-9145,1745-7270
DOI: 10.1093/abbs/gmr090